Basal Ganglia-Cortical Neurophysiology

ECoG During Deep Brain Stimulation Surgery: Safety Experience From 4 Centers Within the NINDS Research Opportunities in Human Consortium. 

Sisterson ND, Carlson AA, Rutishauser U, Mamelak AN, Flagg M, Pouratian N, Salimpour Y, Anderson WS, Richardson RM. Neurosurgery. 2021. 

Movement-Related Coupling of Human Subthalamic Nucleus Spikes to Cortical Gamma

Fischer P, Lipski WJ, Neumann WJ, Turner RS, Fries P, Brown P, Richardson RM. eLife. 2020

Subthalamic Nucleus Activity Influences Sensory and Motor Cortex during Force Transduction

Alhourani A, Korzeniewska, Wozny TA, Lipski WJ, Kondylis ED, Ghuman AS, Crone NE, Crammond DJ, Turner RS, Richardson RM. Cerebral Cortex. 2020. 

Subthalamic Nucleus and Sensorimotor Cortex Activity During Speech Production. 

Chrabaszcz A, Neumann WJ, Stretcu O, Lipski WJ, Bush A, Dastolfo-Hromack C, Wang D, Crammond DJ, Shaiman S, Dickey MW, Holt LL, Turner RS, Fiez JA, Richardson RM. Journal of Neuroscience. 2019.

Subthalamic Nucleus Neurons Differentially Encode Early and Late Aspects of Speech Production. 

Lipski WJ, Alhourani A, Pirnia T, Jones PW, Dastolfo-Hromack C, Helou LB, Crammond DJ, Shaiman S, Dickey MW, Holt LL, Turner RS, Fiez JA, Richardson RM. 

Journal of Neuroscience. 2018.


Dynamics of Human Subthalamic Neuron Phase-locking to Motor and Sensory Cortical Oscillations During Movement.  

Lipski WJ, Wozny TA, Alhourani A, Kondylis E, Turner RS, Crammond DJ, Richardson RM. Journal of Neurophysiology. 2017.

Movement-related Dynamics of Cortical Oscillations in Parkinson’s Disease and Essential Tremor. 

Kondylis ED, Randazzo MJ, Alhourani A, Lipski WJ, Wozny TA, Ghuman AS, Turner RS, Crammond DJ, Richardson RM. Brain. 2016.

Three-dimensional Localization of Cortical Electrodes in Deep Brain Stimulation Surgery from Intraoperative Fluoroscopy. 

Randazzo MJ, Kondylis ED, Alhourani A, Wozny TA, Lipski WJ, Crammond DJ, Richardson RM. Neuroimage. 2016.



Quantifying a frequency modulation response biomarker in responsive neurostimulation. 

Venkatesh P, Sneider D, Danish M, Sisterson ND, Zaher N, Urban A, Grover P, Richardson RM, Kokkinos V. J Neural Eng. 2021.

Ictal Onset Signatures Predict Favorable Outcomes of Laser Thermal Ablation for Mesial Temporal Lobe Epilepsy

Zaher N, Urban A, Antony A, Plummer C, Bagic A, Richardson RM, Kokkinos V. Frontiers in Neurology. 2020


Ex Vivo Mesoscopic Diffusion MRI Correlates with Seizure Frequency in Patients with Uncontrolled Mesial Temporal Lobe Epilepsy

Ke J, Foley LM, Hitchens TK, Richardson RM, Modo M. Human Brain Mapping. 2020. 

Mesoscale Diffusion Magnetic Resonance Imagine of the Ex Vivo Human Hippocampus

Ly M, Foley L, Manivannan A, Hitchens TK, Richardson RM, Modo M. Human Brain Mapping. 2020.

Interpretation of the Intracranial Stereoelectroencephalography Signal

Kokkinos V. Neurosurgery Clinics. 2020

Neuromodulation of Epilepsy Networks

Sisterson ND, Kokkinos V. Neurosurgery Clinics. 2020

Decision Making in Epilepsy Surgery

Richardson RM. Neurosurgery Clinics. 2020

The Hippocampal Barque: An Epileptiform but Non-epileptic Hippocampal Entity

Kokkinos V, Richardson RM, Urban A. Frontiers in Human Neuroscience. 2020

Responsive Neurostimulation of the Thalamus Improves Seizure Control in Idiopathic Generalized Epilepsy

Kokkinos V, Urban A, Sisterson N, Li N, Corson D, Richardson RM. Neurosurgery. 2020.

A Rational Approach to Understanding and Evaluating Responsive Neurostimulation

Sisterson ND, Wozny TA, Kokkinos V, Bagic A, Urban AP, Richardson RM. Neuroinformatics. 2020.

GABA Bouton Subpopulations in the Human Dentate Gyrus Are Differentially Altered in Mesial Temporal Lobe Epilepsy.

Alhourani A, Fish KN, Wozny TA, Sudhakar V, Hamilton RL, Richardson RM. J Neurophysiol. 2019.

The Intracranial Correlate of the 14&6/sec Positive Spikes Normal Scalp EEG Variant.

Kokkinos V, Zaher N, Antony A, Bagić A, Richardson RM, Urban A. Clin Neurophysiol. 2019.

Association of Closed-Loop Brain Stimulation Neurophysiological Features With Seizure Control Among Patients With Focal Epilepsy. 

Kokkinos V, Sisterson ND, Wozny TA, Richardson RM.  JAMA Neurology. 2019. 

Closed-Loop Brain Stimulation for Drug-Resistant Epilepsy: Towards an Evidence-Based Approach to Personalized Medicine. 

Sisterson ND, Wozny TA, Kokkinos V, Constantino A, Richardson RM. Neurotherapeutics. 2019.

Effects of Hippocampal Low-frequency Stimulation in Idiopathic Non-human Primate Epilepsy Assessed via a Remote-sensing-enabled Neurostimulator.  

Wozny TA, Lipski WJ, Alhourani A, Kondylis ED, Antony A, Richardson RM. Experimental Neurology. 2017.

Detection of Aberrant Hippocampal Mossy Fiber Connections: Ex Vivo Mesoscale Diffusion MRI and Microtractography with Histological Validation 

Modo M, Hitchens TK, Liu JR, Richardson RM. Humain Brain Mapping. 2016.

Short-term Neurocognitive Outcomes Following Anterior Temporal Lobectomy.  

Lee PS, Pardini J, Hendrickson R, Destefino V, Popescu A, Ghearing G, Antony A, Pan J, Bajic A, Wagner D, Richardson RM. Epilepsy and Behavior. 2016.

Sensing-enabled Hippocampal Deep Brain Stimulation in Idiopathic Nonhuman Primate Epilepsy.  

Lipski WJ, DeStefino VJ, Stanslaski SR, Antony AR, Crammond DJ, Cameron JL, Richardson RM. Journal of Neurophysiology. 2015.

Detection of High-frequency Oscillations by Hybrid Depth Electrodes in Standard Clinical Intracranial EEG Recordings. 

Kondylis ED, Wozny TA, Lipski WJ, Popescu A, DeStefino VJ, Esmaeili B, Raghu VK, Bagic A, Richardson RM. Frontiers in Neurology. 2014.

Movement Disorders

Association of Preoperative Visual Hallucinations With Cognitive Decline After Deep Brain Stimulation for Parkinson's Disease.

Kratter IH, Karp JF, Chang YF, Whiteman AC, Feyder MT, Jorge A, Richardson RM, Henry LC. J Neuropsychiatry Clin Neurosci. 2020

Anterior Sensorimotor Subthalamuc Nucleus Stimulation is Associated With Improved Voice Function

Jorge A, Dastolfo-Hromack C, Lipski WJ, Kratter IH, Smith LJ, Gartner-Schmidt JL, Richardson RM. Neurosurgery. 2020


Robotic-Assisted Stereotaxy for Deep Brain Stimulation Lead Implantation in Awake Patients

Faraji AH, Kokkinos V, Sweat JC, Crammond DJ, Richardson RM. Operative Neurosurgery. 2020

Toward Electrophysiology-Based Intelligent Adaptive Deep Brain Stimulation for Movement Disorders

Neumann WJ, Turner RS, Blankertz B, Mitchell T, Kühn AA, Richardson  RM. Neurotherapeutics. 2019.

Outcomes of Interventional-MRI Versus Microelectrode Recording-Guided Subthalamic Deep Brain Stimulation. 

Lee PS, Weiner GM, Corson D, Kappel J, Chang Y, Suski VR, Berman SB, Homayoun H, Van Laar AD, Crammond DJ, Richardson RM. Frontiers in Neurology. 2018.

Network Effects of Deep Brain Stimulation. 

Alhourani A, McDowell MM, Randazzo MJ, Wozny TA, Kondylis ED, Lipski WJ, Beck S, Karp JF, Ghuman AS, Richardson RM. Journal of Neurophysiology. 2015.

Cognitive Neuroscience Collaborations 

Endogenous Activity Modulates Stimulus and Circuit-Specific Neural Tuning and Predicts Perceptual Behavior

Li Y, Ward MJ, Richardson RM, G'Sell M, Ghuman AS. Nature Communications. 2020

Posterior Fusiform and Midfusiform Contribute to Distinct Stages of Facial Expression Processing. 

Li Y, Richardson RM, Ghuman AS. Cerebral Cortex. 2018.

Multi-Connection Pattern Analysis: Decoding the Representational Content of Neural Communication. 

Li Y, Richardson RM, Ghuman AS. Neuroimage. 2017.

Associative Experiential Phenomena Result from Stimulating Left Ventromedial Temporal Cortex. 

Aminoff E; Li Y; Pyles JA; Ward MJ; Richardson RM; Ghuman AS. Cortex. 2016.

Decoding and Disrupting Left Mid-fusiform Gyrus Activity During Word Reading.

Hirshorn EA , Li Y, Ward MJ, Richardson RM, Fiez J, Ghuman AS. PNAS. 2016.

Dynamic Encoding of Face Information in the Human Fusiform Gyrus.  

Ghuman AS, Brunet NM, Li Y, Konecky RO, Pyles JA, Walls SA, Destefino V, Wang W, Richardson RM. Nature Communications. 2014.