GENE AND CELL THERAPY

Neurosurgical gene therapy for central nervous system diseases.
Patel RV, Nanda P, Richardson RM. Neurotherapeutics. 2024

Safety of AADC Gene Therapy for Moderately Advanced Parkinson Disease: Three-Year Outcomes From the PD-1101 Trial
Christine CW, Richardson RM, Van Laar AD, Thompson ME, Fine EM, Khwaja OS, Li C, Liang GS, Meier A, Roberts EW, Pfau ML, Rodman JR, Bankiewicz KS, Larson PS. Neurology. 2022.

Data-driven evolution of neurosurgical gene therapy delivery in Parkinson's disease
Richardson RM, Bankiewicz KS, Christine CW, Van Laar AD, Gross RE, Lonser R, Factor SA, Kostyk SK, Kells AP, Ravina B, Larson PS. J Neurology Neurosurgery Psychiatry. 2020.

Aromatic L-Amino Acid Decarboxylase Gene Therapy Enhances Levodopa Response in Parkinson's Disease
Nutt JG, Curtze C, Hiller A, Anderson S, Larson PS, Van Laar AD, Richardson RM, Thompson ME, Sedkov A, Leinonen M, Ravina B, Bankiewicz KS, Christine CW. Movement Disorders. 2020

Magnetic resonance imaging-guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease
Christine CW, Bankiewicz KS, Van Laar AD, Richardson RM, Ravina B, Kells AP, Boot B, Martin AJ, Nutt J, Thompson ME, Larson PS. Annals of Neurology. 2019.

Gene Therapy for Neurodegenerative Diseases
Sudhakar V, Richardson RM. Neurotherapeutics. 2019.

Gene Therapy for Parkinson's Disease
Sudhakar V, Richardson RM. Progress in Neurological Surgery. 2018.

Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain
Richardson RM, Kells AP, Martin AJ, Larson PS, Starr PA, Piferi PG, Bates G, Tansey L, Rosenbluth KH, Bringas JR, Berger MS, Bankiewicz KS. Stereotactic & Functional Neurosurgery. 2011.

Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease
Richardson RM, Kells AP, Rosenbluth KH, Salegio EA, Fiandaca MS, Larson PS, Starr PA, Martin AJ, Lonser RR, Federoff HJ, Forsayeth JR, Bankiewicz KS. Molecular Therapy. 2011.